和来曲唑用于多囊卵巢综合征促排卵中的临床疗效观察,本文关于来曲唑论文范文,可以做为相关论文参考文献,与写作提纲思路参考。
来曲唑论文参考文献：
【摘 要】 目的 比較（CC）与来曲唑（LE）对多囊卵巢综合征（PCOS）患者促排卵治疗的作用及妊娠结局.方法 200例PCOS患者, 随机分为LE组（90例）和CC组（110例）.两组均于月经周期第3～7天分别服用LE与CC, 观察LE与CC对卵泡发育、子宫内膜及妊娠结局的影响.结果 LE组出现优势卵泡79例（87.78%）多于CC组的44例（40.00%）, 差异有统计学意义（P<0.05）.LE组单卵泡发育74例（93.67%）多于CC组15例（34.09%）, 差异有统计学意义（P<0.05）.LE组优势卵泡绒毛膜促性腺激素（HCG）注射日子宫内膜平均厚度为（8.28±1.89）mm, 优于CC组的（5.79±1.49）mm, 差异有统计学意义（P<0.05）.CC组妊娠6例, 妊娠率为5.45%；LE组妊娠25例, 妊娠率为27.78%；LE组妊娠率明显高于CC组, 差异有统计学意义（P<0.05）.CC组治疗中卵巢过度刺激综合征（OHSS）发生2例, LE 组发生1例, 均为轻度；CC组临床妊娠中出现2例多胎, LE 组出现1例多胎；两组OHSS发生率和多胎妊娠发生率比较差异无统计学意义（P>0.05）.结论 于月经周期第3～7 天服用LE, 使胚胎着床情况更佳, 妊娠率明显升高, 值得在临床中加以推广应用.
【关键词】 来曲唑；；多囊卵巢综合征；促排卵
DOI：10.14163/j.cnki.11-5547/r.2017.27.004
【Abstract】 Objective To compare the effects of clomiphene （CC） and letrozole （LE） on ovulation induction in patients with polycystic ovary syndrome （PCOS） and pregnancy outcome. Methods A total of 200 PCOS patients were randomly divided into LE group （90 cases） and CC group （110 cases）. Both groups were treated with LE and CC respectively on 3rd～7th day of menstrual cycle, and the effects of LE and CC on follicular development, endometrium and pregnancy outcome were observed. Results LE group had more number of dominant follicle as 79 cases （87.78%） than 44 cases （40.00%） in CC group, and the difference was statistically significant （P<0.05）. LE group had more number of single follicular development as 74 cases （93.67%） than 15 cases （34.09%）in CC group, and the difference was statistically significant （P<0.05）. LE group had better average thickness of endometrium injected by human chorionic gonadotropin （HCG） in dominant follicle as （8.28±1.89） mm than （5.79±1.49） mm in CC group, and the difference was statistically significant （P<0.05）. CC group had 6 pregnancy cases, with pregnancy rate as 5.45%, while LE group had 25 pregnancy cases, with pregnancy rate as 27.78%. LE group had obviously higher pregnancy rate than CC group, and the difference was statistically significant （P<0.05）. CC group had 2 ovariy hyperstimulation s yndrome （OHSS） cases during treatment, which was 1 case in LE group, and all were mile cases. CC group had 2 multiple birth cases, which was 1 case in LE group. Both groups had no statistically significant difference in incidence of OHSS and multiple pregnancy （P>0.05）. Conclusion Taking LE on 3rd～7th day of menstrual cycle can help embryo implantation and obviously increase pregnancy rate. It is worth clinical popularizing and applying.
【Key words】 Letrozole； Clomiphene； Polycystic ovary syndrome； Ovulation induction
结论：关于本文可作为来曲唑方面的大学硕士与本科毕业论文来曲唑论文开题报告范文和职称论文论文写作参考文献下载。
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